Prazosin, sold under the brand name Minipress, is a prescription medication used to treat high blood pressure.
The drug may also be used to treat patients with an enlarged prostate, congestive heart failure, Raynaud’s disease, pheochromocytoma, and Ergot alkaloid poisoning.
Some doctors prescribe prazosin to people with post-traumatic stress disorder, as it blocks the body’s release of the hormone adrenaline.
Prazosin is one drug in the class of alpha-adrenergic blockers, which work by relaxing the blood vessels so that blood can pass through more easily.
Prazosin comes in a tablet and capsule form and is manufactured by Pfizer, Inc.
Prazosin Warnings You may feel dizzy when you first start prazosin, since it lowers blood pressure.
This effect usually stops once your body gets used to the medication.
Try not to stand up too quickly.
Older patients may be more sensitive to the side effects of prazosin, especially dizziness and fainting, which can increase the risk of falling.
Before taking this drug, you should tell your doctor if you have a history of the following conditions: Heart problems Low blood pressure Kidney disease Narcolepsy Prostate cancer You should tell your doctor that you are taking this medication before having surgery, including eye surgery.
Don’t stop taking prazosin without first consulting your physician.
Because some conditions may worsen when the medication is stopped abruptly, your dose may need to be gradually decreased.
Pregnancy and Prazosin Prazosin should only be used during pregnancy if absolutely necessary.
The drug passes through breast milk.
BasicDescription Back to Top Prazosin Side Effects Common Side Effects of Prazosin: Some less serious side effects of prazosin include: Weakness Tiredness Dizziness Nausea Serious Side Effects of Prazosin: You should call your doctor if you experience any of the following serious side effects: Fast or pounding heartbeat or fluttering in your chest Feeling like you might pass out Trouble breathing Swelling in the hands, ankles, or feet An erection that is painful or lasts four or more hours Back to Top Prazosin Interactions Prazosin and Other Drug Interactions Some drugs that may interact with prazosin include: Beta blockers, such as atenolol (Tenormin), metoprolol (Toprol-XL), propranolol ( Inderal ) Verapamil (Calan) Erectile dysfunction or pulmonary hypertension meds Antihistamines, such as diphenhydramine (llermax, Banophen, Benadryl ) Anti-seizure drugs, such as carbamazepine (Carbatrol, Epitol, Equetro, Tegretol ) Drugs for sleep or anxiety, such as alprazolam (Niravam, Xanax, Xanax XR), diazepam (Valium), zolpidem (Ambien) Muscle relaxants Narcotic pain relievers (such as codeine ) Psychiatric meds, such as chlorpromazine ( Thorazine ), risperidone (Risperdal), amitriptyline (Elavil), trazodone (Desyrel) Check the labels on all of your medications because they may contain ingredients that can increase your blood pressure or cause a fast heartbeat.
This drug may also interfere with certain lab tests, so you should tell laboratory personnel you are taking prazosin.
You should also discuss all prescription, non-prescription, illegal, recreational, herbal, nutritional or dietary drugs you are taking with your doctor.
Prazosin and Other Interactions This drug may impair your vision and make you dizzy or drowsy.
Do not drive, use machinery, or perform any other activity that requires alertness until you are sure you can do so safely.
You should also limit your alcohol intake while taking prazosin.
Back to Top Prazosin Dosage The amount of prazosin you take will depend on your doctor’s instructions.
A typical dosing schedule may look like this: For high blood pressure : Adults: Start with 0.5-1 milligrams (mg), two or three times a day.
Then, your doctor will slowly increase your dose to 6-15 mg, divided into two or three doses a day.
However, the total daily dose is usually not more than 20 mg.
Children: The dose will be based on body weight.
The usual dose is 50-400 micrograms per kilogram of body weight a day.
This is typically divided into two or three doses.
Prazosin Overdose If you suspect an overdose, contact a poison control center at (800) 222-1222 or an emergency room immediately.
Missed Prazosin If you miss a dose of prazosin, take it as soon as you remember.
If it is close to the time of the next dose, skip the missed dose and resume your usual dosing schedule.
Do not “double up” and take more than one dose at a time.
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