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Additional information about the drug Phenytoin

Dilantin is the brand name of the drug phenytoin, which is used to treat seizures.
The medication is also used to prevent seizures after brain surgery The drug is in a class of medications known as anticonvulsants.
It works by decreasing abnormal electrical activity in the brain.
Dilantin was originally approved for use in seizures by the Food and Drug Administration (FDA) in 1953 and is manufactured by Pfizer, Inc.
Dilantin Warnings You shouldn’t take Dilantin if you also take delavirdine (Rescriptor), or if you are allergic to phenytoin, ethotoin (Peganone), fosphenytoin (Cerebyx), or mephenytoin (Mesantoin).
This medication may change your mental health in unexpected ways.
Some people who take Dilantin become suicidal.
You or your caregiver should tell your doctor right away if you experience any of the following symptoms: Thinking or talking about suicide Agitation or restlessness Irritability Depression Anxiety Panic attacks Violent behavior Withdrawing from friends and family Mania (an abnormally excited mood) Dilantin may increase your blood sugar levels.
You should talk to your doctor about symptoms of high blood sugar and what to do if you experience them.
This drug can also increase your risk for developing osteomalacia (weakening and softening of bones) and Hodgkin lymphoma (cancer that begins in the lymph nodes).
You may also experience swollen lymph nodes while taking Dilantin.
You should discuss these risks with your physician.
Dilantin may also cause swelling and bleeding of the gums and could increase your risk of gum damage.
You should discuss proper ways to care for your teeth and gums while taking this drug.
Before taking this medicine, you should tell your doctor if you have or have ever had: Diabetes Lupus A folate or vitamin B-12 deficiency Porphyria (a rare, inherited condition that affects the functioning of your blood’s hemoglobin) Kidney disease Liver disease You should also tell your physician if you are an alcoholic or have ever consumed large amounts of alcohol.
In case of emergency, you may want to wear a medical alert tag or carry an ID card that says you take Dilantin, so medical care providers are aware.
Tell your doctor you are taking Dilantin before having any kind of surgery, including dental procedures.
A number of clinical and anecdotal reports have linked anticonvulsants such as Dilantin to Stevens-Johnson syndrome, a rare but serious disorder of the skin and mucous membranes.
Symptoms of Stevens-Johnson syndrome include hives, swelling of the face and tongue, rash, skin irritation and shedding, and blisters.
Dilantin Toxicity Serious toxicity can occur in people who take Dilantin.
This is more likely to happen when doses are increased or other medications are started or stopped.
Common symptoms of Dilantin toxicity include dizziness, drowsiness, coordination problems, rapid eye movements, and extreme fatigue.
Pregnancy and Dilantin Dilantin is a pregnancy category D drug, which means it may harm an unborn baby.
However, having a seizure during pregnancy could also harm the unborn baby and mother.
You shouldn’t start taking Dilantin if you are pregnant unless your doctor tells you to do so.
If you become pregnant while taking Dilantin, don’t stop taking the drug without first talking to your doctor.
This drug may also make some methods of birth control less effective.
You should talk to your doctor about using non-hormonal birth control options to prevent pregnancy while taking Dilantin.
Dilantin can pass into breast milk and may harm a breastfeeding baby.
You shouldn’t breastfeed while taking this drug.
BasicDescription Back to Top Dilantin Side Effects Common Side Effects of Dilantin You should tell your doctor if any of the following symptoms become severe or don’t go away: Uncontrollable eye movements or abnormal body movements Difficulty falling asleep or staying asleep Confusion or slowed thinking Loss of coordination Slurred speech Dizziness Headache Nausea, vomiting, or constipation Lip enlargement Gum overgrowth Unwanted hair growth Facial changes Pain or curving of the penis Serious Side Effects of Dilantin You should call your doctor immediately if you experience any of the following serious side effects: Fever Blisters or rash Swollen glands Joint pain Yellowing of the eyes or skin Pain in the upper right part of the stomach Excessive fatigue Unusual bleeding or bruising Flu -like symptoms Loss of appetite Back to Top Dilantin Interactions There are many drugs that may interact with Dilantin.
Before starting it, tell your doctor about all prescription, non-prescription, illegal, recreational, herbal, nutritional, or dietary drugs you’re taking, especially: Antacids that contain calcium (Maalox, Mylanta, Tums, others) Amiodarone (Cordarone, Pacerone) Anticoagulants (blood thinners) such as warfarin ( Coumadin ) Certain antidepressants including amitriptyline (Elavil), amoxapine (Asendin), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Sinequan), imipramine (Tofranil), maprotiline, nortriptyline (Pamelor), protriptyline (Vivactil), and trimipramine (Surmontil) Chloramphenicol Chlordiazepoxide ( Librium ) Diazepam (Valium) Digoxin (Lanoxin) Disulfiram ( Antabuse ) Doxycycline (Doryx, Monodox, Vibramycin, others) Fluoxetine ( Prozac, Sarafem, in Symbyax) Furosemide ( Lasix ) H2 antagonists such as cimetidine (Tagamet), famotidine ( Pepcid ), nizatidine (Axid), and ranitidine ( Zantac ) Hormonal contraceptives (birth control pills, patches, rings, or injections) Hormone replacement therapy (HRT) Isoniazid (in Rifamate, in Rifater) Drugs for mental illness and nausea Other medications for seizures such as carbamazepine (Carbatrol, Equetro, Tegretol ), ethosuximide (Zarontin), methsuximide (Celontin), phenobarbital, and valproic acid (Depacon, Depakene, Stavzor) Methylphenidate (Daytrana, Concerta, Metadate, Ritalin ) Molindone (Moban) Oral steroids such as dexamethasone ( Decadron, Dexone), methylprednisolone (Medrol), prednisolone, and prednisone (Deltasone) Paroxetine (Paxil, Pexeva) Quinidine Reserpine (Serpalan) Rifampin (Rimactane, in Rifamate, in Rifater) Salicylate pain relievers such as aspirin, choline magnesium trisalicylate, choline salicylate (Arthropan), diflunisal (Dolobid), magnesium salicylate (Doan’s, others), and salsalate (Argesic, Disalcid, Salgesic) Sucralfate (Carafate) Sulfa antibiotics Theophylline (Theo-Dur) Ticlopidine (Ticlid) Tolbutamide Trazodone Vitamin D Dilantin and Alcohol Alcohol may interfere with Dilantin.
You should talk to your doctor about how much alcohol is safe to consume while taking this drug.
Dilantin and Other Interactions Dilantin may cause dizziness and coordination trouble.
You shouldn’t drive or operate machinery until you know how this medication will affect you.
Back to Top Dilantin Dosage Dilantin comes as a chewable tablet, an extended-release tablet, and a liquid to take by mouth.
The recommended adult dose is typically 100 milligrams (mg), two to four times a day.
Some patients may require 200 mg, three times a day.
The liquid and chewable tablets are typically taken two or three times a day.
The capsules are usually taken one to four times a day.
Swallow the extended-release capsules whole.
Don’t crush, chew, or split them.
Also, don’t take the capsules if they are discolored.
You can chew or swallow the chewable tablets.
Shake the liquid form of this medicine well before each dose.
Your doctor will probably start you on a low dose of Dilantin and gradually increase it.
Try to take this medication at around the same time each day.
Follow the instructions on your prescription label carefully.
Don’t take more or less of this drug than is prescribed.
Dilantin Overdose If you suspect an overdose, you should contact a poison control center or emergency room immediately.
You can get in touch with a poison control center at (800) 222-1222.
Missed Dose of Dilantin If you miss a dose of Dilantin, take it as soon as you remember.
However, if it’s almost time for your next dose, skip the missed dose and continue on your regular dosing schedule.
Don’t double up on doses to make up for a missed one.
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