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Additional information about the drug Prograf

Prograf is used along with other medications to prevent rejection (attack of a transplanted organ by the immune system of a person receiving the organ) in people who have received kidney, liver, or heart transplants. It is also used as a topical agent for treating eczema that has not responded to other medications.
Prograf is in a class of medications called immunosupressants. It works by decreasing the activity of the immune system.
This medication comes in an immediate-release capsule form that is taken twice a day and extended-release capsule and tablet forms that are taken once a day. It is also available as an injectable form that is given as an ongoing infusion after the transplant surgery.
Prograf is also available as a topical ointment that is applied to the affected skin twice a day.
Common side effects of oral and injectable tacrolimus include infection, altered renal function, increased blood pressure, headache, tremor, and nausea. Common side effects of topical tacrolimus include soreness or irritation at the application site.
Prograf can also cause blurred vision, drowsiness, and dizziness. Do not drive or operate heavy machinery until you know how tacrolimus affects you.
Prograf is used along with other medications to prevent rejection (attack of a transplanted organ by the immune system of a person receiving the organ) in people who have received kidney, liver, or heart transplants. It works by decreasing the activity of the immune system to prevent it from attacking the transplanted organ.
Prograf is used for treating eczema that has not responded to other medications. It works by stopping the immune system from producing substance that may cause eczema.
This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.
Prograf may be found in some form under the following brand names:
Prograf is part of the drug class:
Serious side effects have been reported with Prograf. See the “Prograf Precautions” section.
Common side effects of oral and injectable tacrolimus include the following:
Common side effects of topical tacrolimus include the following:
This is not a complete list of tacrolimus side effects. Ask your doctor or pharmacist for more information.
Topical calcineurin inhibitors, such as tacrolimus 0.1% ointment, have been shown to be effective in CLE and offer a decreased risk of telangiectasia development compared with topical steriods.

  • IRs of lymphoma per 100,000 person-years were 10.4 events in children and 41.0 events in adults using tacrolimus and 3.0 events in children and 27.0 events in adults using pimecrolimus.
  • Topical tacrolimus and pimecrolimus have recently been FDA-approved for the treatment of AD.
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