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Lisinopril is the generic form of the brand-name drug Zestril, a medication prescribed to treat high blood pressure.
Doctors also prescribe lisinopril in combination with other drugs to treat congestive heart failure.
Lisinopril is in a class of medications called angiotensin-converting enzyme inhibitors, or ACE inhibitors.
It works by widening blood vessels, which allows blood to flow more smoothly and lets the heart function more efficiently.
By lowering blood pressure, lisinopril also helps reduce the risk for stroke and heart attack.
The Food and Drug Administration (FDA) first approved lisinopril in 1987.
The drug company Merck developed lisinopril under the brand name Prinivil.
In 2002, the FDA approved generic lisinopril.
Lisinopril Warnings If you take medication or insulin to treat diabetes, track your blood sugar carefully while also taking lisinopril, particularly during the first month of its use.
The combination of these diabetes drugs can cause a drop in your blood sugar levels.
It’s also important to be aware of any signs of infection, such as sore throat or fever, which could indicate problems with your white blood cell count.
Before starting on lisinopril, be sure to let your doctor know if you have any type of surgery planned, including dental surgery.
Tell your doctor if you have angioedema, a condition that causes trouble swallowing or breathing as well as painful swelling in various parts of the body, including the face, throat, eyes, hands, feet, ankles, and lower legs.
You should also let your doctor know if you have diabetes and are taking aliskiren (Tekturna, Amturnide, Tekamlo, Tekturna HCT).
Your doctor also needs to know if you’ve ever had: Heart or kidney disease Lupus Scleroderma Pregnancy and Lisinopril There’s strong evidence that lisinopril can harm an unborn baby.
Make sure your doctor knows if you are pregnant, or may become pregnant, before taking lisinopril.
If you get pregnant while taking lisinopril, call your doctor right away.
It’s unknown whether the drug passes into a woman’s breast milk, but to be safe, women who are breastfeeding should stop breastfeeding (or not take lisinopril).
Research shows that lisinopril is safe and effective for children older than 6 and for teenagers.
There’s not enough evidence to say that it’s safe for younger children.
BasicDescription Back to Top Lisinopril Side Effects Common side effects of lisinopril include: Cough Dizziness Headache Extreme tiredness Nausea Diarrhea Weakness Sneezing Runny nose Low sex drive Rash Serious side effects can also occur.
If you have any of these side effects, call your doctor right away: Swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs Hoarseness Trouble breathing or swallowing Signs of infection, such as fever, sore throat, and chills Yellowing of the skin or eyes Lightheadedness or fainting Chest pain Back to Top Lisinopril Interactions Some drugs may affect the way lisinopril works, and lisinopril could also affect other medications.
It’s very important to let your doctor know about everything you are taking, including any over-the-counter (OTC) medications, herbs, or supplements as well as illegal drugs.
Drugs that interact with lisinopril include: Aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs ), such as indomethacin (Indocin) Diuretics (“water pills”) Potassium supplements Medications for diabetes, such as insulin and aliskiren (Tekturna, Amturnide, Tekamlo, Tekturna HCT) The antidepressant lithium (Eskalith, Lithobid) Other ACE inhibitors Lisinopril and Alcohol People taking lisinopril are advised to avoid drinking alcohol.
Alcohol can also lower your blood pressure, and may increase your risk of certain side effects of lisinopril.
Other Lisinopril Interactions It’s important to talk to your doctor before using any salt substitutes that contain potassium when you’re taking lisinopril.
Your doctor may also tell you to follow a low-salt or low-sodium diet.
It’s important to follow these directions carefully.
Back to Top Lisinopril Dosage Lisinopril is a tablet that you take orally.
It’s available in various strengths, ranging from 2.5 milligrams (mg) to 40 mg.
You’ll typically take lisinopril once a day, around the same time each day.
Your doctor will probably prescribe a low dose of the drug at first and gradually increase it over time.
For people with high blood pressure, the typical dose of lisinopril ranges from 20 to 40 mg a day.
When treating heart failure, the effective dose of the drug ranges from 5 to 40 mg a day.
For people who’ve had a heart attack, the first dose of lisinopril is 5 mg.
After 24 hours, you’ll take another 5 mg.
After 48 hours, you’ll take 10 mg a day for six weeks.
For children, the usual starting dose of lisinopril is up to 5 mg daily.
Lisinopril Overdose Taking too much lisinopril would most likely lead to low blood pressure.
Symptoms of a lisinopril overdose could include: Lightheadedness Fainting If you or someone else has symptoms of an overdose, call a poison control center at 1-800-222-1222.
If someone collapses or isn’t breathing, call 911.
Missed Dose of Lisinopril Keep taking lisinopril, even if you feel well.
Don’t stop taking lisinopril without talking to your doctor first.
If you miss a dose of lisinopril, take the missed dose as soon as you remember it.
If it’s close to your next scheduled dose of the drug, skip the missed dose.
Don’t take twice as much lisinopril at one time to make up for a missed dose.
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