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Additional information about the drug Naprelan

Naprelan sodium is the generic ingredient in Aleve and several other brands of pain medication.
Naprelan is in a class of drugs called non-steroidal anti-inflammatory drugs (NSAIDs), which work by blocking the production of prostaglandins, substances in the body that play a role in pain and inflammation.
Naprelan has been used in the United States since 1980.
It is available generically and under many brand names.
After 14 years as a prescription-only medication, in 1994 naproxen was approved by the Food & Drug Administration (FDA) as an over-the-counter (OTC) drug.
The best-known brand name for OTC naproxen is Aleve, which is made by the Bayer Healthcare.
Other brand names for naproxen include Anaprox DS, Naprelan, Anaprox, EC-Naprosyn, and Naprosyn.
As a prescription-strength drug, naproxen comes in the form of tablets or as a liquid.
Tablets may be coated to protect your stomach, or they may be extended-release tablets that you need to take only once a day.
Prescription-strength naproxen is often used to treat joint pain, menstrual pain, rheumatoid arthritis, gout, ankylosing spondylitis, juvenile arthritis, tendonitis, and bursitis.
Nonprescription naproxen is commonly used to relieve pain, swelling, fever, cold and flu symptoms, and headaches.
Naprelan Warnings Naprelan may raise your risk for heart attacks and stroke.
Heart and stroke risk is greater if you have a history of or risk factors for heart disease.
Naprelan may cause ulcers and bleeding in your gastrointestinal (GI) tract.
Ulcer and bleeding risk is higher if you are elderly.
Because elderly people are more likely to have side effects, you should take the lowest possible effective dose if you are over age 65.
Usual adult dose for pain is 250 every 6 to 8 hours or 500 mg twice daily using regular naproxen tablets.

  • FKL Chan et al. Gastrointestinal safety of celecoxib versus naproxen in patients with cardiothrombotic diseases and arthritis after upper gastrointestinal bleeding (CONCERN): an industry-independent, double-blind, double-dummy, randomised trial.
  • The linearity for Piroxicam was in the range of 3a??200 I?g.mL-1 and for Naprelan and Mefenamic acid was in the range 1-200 I?g.mL-1, while for Diclofenac sodium was in the range 1.5a??200 I?g.mL-1. The proposed method was successfully applied for the determination of these drugs in their pure form and different pharmaceutical preparations (tablets, capsules, and ampoule and there is no interference with additives.
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