Aciphex is a prescription medication used to treat digestive problems such as heartburn and acid reflux. Aciphex belongs to a group of drugs called proton-pump inhibitors (PPIs). It works by reducing the amount of acid produced in the stomach.
Aciphex comes in a delayed release tablet and is usually taken once a day. Swallow rabeprazole tablets whole. Do not chew, crush or split rabeprazole tablets.
Aciphex also comes in a sprinkle delayed release capsule and is usually taken once a day.
Common side effects of rabeprazole include headache, sore throat, and constipation.
CYP2C19 is an enzyme in the blood that is responsible for breaking down rabeprazole and other drugs in the body. Some patients have less of this protein in their bodies, affecting how much of the drug gets eliminated. Levels of CYP2C19 can vary greatly between individuals, and those having less of this protein are known as “poor metabolizers.”
CYP2C19 testing is done to determine whether you are a poor metabolizer. If you are a poor metabolizer, the levels of rabeprazole in your blood can become too high. As a result you may be at an increased risk of having more side effects from rabeprazole.
Your doctor may adjust your dose of rabeprazole if you are a poor metabolizer.
Aciphex is a prescription medicine used for the following conditions:
This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.
Aciphex may be found in some form under the following brand names:
Aciphex is part of the drug class:
Serious side effects have been reported with rabeprazole. See the “Drug Precautions” section.
Common side effects with rabeprazole include the following
People who are taking multiple daily doses of proton pump inhibitor medicines for a long period of time may have an increased risk of fractures of the hip, wrist, or spine.
This is not a comple list of rabeprazole side effects. Ask your doctor or pharmacist for more information.
Aciphex is a proton pump inhibitor sold its sodium salt) under brand name Aciphex and Pariet.
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A model including medical costs for hospitalizations, procedures, and office visits was developed ( Ofman et al 2000 ) to compare the cost-effectiveness of rabeprazole and ranitidine in acute and maintenance therapy for erosive esophagitis using symptom response, rather than endoscopic healing, as the clinical outcome.
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